The Effect of Amniotic Membrane Transplantation for Corneal Ulcer and Ocular Surface Diseases

PURPOSE: To describe the clinical outcome of AMT (amniotic membrane transplantation) for corneal ulcers, persistent epithelial defects, corneal perforations, and neurotropic ulcers. METHODS: We performed AMT on 10 cases of corneal ulcer, 5 cases of persistent epithelial defect, 2 cases of corneal perforation, and 3 cases of neurotropic ulcer from Agust 1999 to May 2002. Amniotic membrane was obtained from the women undergoing elective Cesarean section or normal delivery. We had applied one or two layers of fresh amniotic membrane, that is used within 4hours after resection, over the ulcer bed and anchored by interrupted and running suture technique with 10-0 Nylon. After AMT, Topical eye drops was used three times a day. RESULTS: After AMT, Visual acuity was improved in 6 eyes of 10 corneal ulcer patients and maintained in 3 eyes. In all patients the persistent epithelial erosion was healed and pain was subsided between 6 and 12 days after surgery. There were no leakage in corneal perforation patients, and stable ocular surface were achieved after mean period 15.5 days. The ocular surface was restored by AMT in all neurotropic ulcer patients. CONCLUSIONS: The AMT is an effective method for managing corneal ulcer or ocular surface diseases, that are refractory to conventional treatment. The AMT shortened the usage of broad spectrum antibiotics , increased compliance, and decreased corneal opacity and neovascularization.

The Effect of Modified Anterior Transposition of the Inferior Oblique Muscle for Hypertropia in Superior Oblique Muscle Palsy with Inferior Oblique Muscle Overaction

PURPOSE: The authers studied the effect of modified anterior transposition of the inferior oblique muscle for hypertropia in superior oblique muscle palsy combined inferior oblique muscle overaction. METHODS: We retrospectively analysed 19 cases of superor oblique palsy, which were treated by modified inferior oblique muscle anterior transposition from January 1999 to march 2001. Mean follow-up was 14.6 months. The medial portion of inferior oblique muscle was transpositioned to 1mm posterior position of the temporal insertion of inferior rectus muscle and lateral portion of inferior oblique muscle was moved 5mm on imaginary line, which is the line of between temporal insertion of inferior rectus and inferior insertion of lareral rectus muscle, to the direction of inferior insertion of lateral rectus muscle from temporal insertion of inferior rectus muscle, then backward 6mm from that point perpendicularly. RESULTS: The success rates in modified anterior transposition were 94% in under 20delta of hypertropia and 89.5% in over +3 of IOOA. CONCLUSIONS: Modified anterior transposition is an effective procedure of +3 to +4 inferior oblique muscle overaction and hypertropia in superior oblique muscle palsy as a primary surgery.

A Case of Chandler's Syndrome Associated with Anterior Uveitis

PURPOSE: To report a case of Chandler's syndrome associated with anterior uveitis. METHODS: We encountered a 39-year-old woman who complained of decreased visual acuity in the left eye with anterior uveitis and increased intraocular pressure. On examination, we found corectopia, endothelial pleomorphism and peripheral anterior synechiae, leading to the diagnosis of Chandler's syndrome with anterior uveitis. RESULTS: The anterior uveitis and increased intraocular pressure in Chandler's syndrome were well controlled with the use of Beta-blocker, Latanoprost and topical corticosteroids. We report this case with a review of the literatures.

A Case of Chandler's Syndrome Associated with Anterior Uveitis

PURPOSE: To report a case of Chandler's syndrome associated with anterior uveitis. METHODS: We encountered a 39-year-old woman who complained of decreased visual acuity in the left eye with anterior uveitis and increased intraocular pressure. On examination, we found corectopia, endothelial pleomorphism and peripheral anterior synechiae, leading to the diagnosis of Chandler's syndrome with anterior uveitis. RESULTS: The anterior uveitis and increased intraocular pressure in Chandler's syndrome were well controlled with the use of Beta-blocker, Latanoprost and topical corticosteroids. We report this case with a review of the literatures.